Moderate drinking may stave off dementia.

Alzheimer's Disease

But too much may do just the opposite, research shows

NEW YORK - Having one or two alcoholic drinks per day may help prevent dementia in the elderly, according to study findings presented Monday at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease in Vienna, Austria. Too much alcohol use, however, may promote dementia.

The results indicate that cognitively normal adults, 75 years or older, who are moderate drinkers are 40 percent less likely to develop dementia over 6 years than are their non-drinking peers. By contrast, alcohol use appears to offer no benefit, and possibly harm, for adults who already have some degree of cognitive impairment.

"We were pleased to see that the beneficial effects of moderate alcohol intake reported in middle-aged adults also extend to cognitively normal older adults over 75," lead author Dr. Kaycee M. Sink, from Wake Forest University School of Medicine in Winston-Salem, North Carolina, told Reuters Health.

Dr. Sink noted that her team's study is not the first to look at the association between alcohol use and the risk of dementia, but said that several factors make it unique.

"It is one of largest, longest studies of older adults living in the U.S. to examine this question; the participants are older than most previously studied; and we were able to look at the effects of alcohol consumption in both cognitively normal older adults as well as those who had mild cognitive impairment."

The subjects included 3,069 adults who were enrolled in the Ginkgo Evaluation of Memory Study (GEMS). Based on extensive testing, the subjects were classified as having normal cognition or mild impairment at baseline. Alcohol use was categorized as none, light, moderate, or heavy, based on having 0, 1 to 7, 8 to 14, or more than 14 drinks per week, respectively.

At the start of the study, 2,587 subjects had normal cognition and 482 had mild cognitive impairment. In terms of alcohol use, about 40 percent were either none or light drinkers, and about 10 percent each were moderate or heavy users.


Taken from: msnbc news